0
Pyruvate enters the Krebs cycle via an intermediate called acetyl CoA.
Pyruvate is formed in the cytoplasm as the end product of glycolysis. Pyruvate enters a mitochondrion, in the matrix of which it encounters the enzyme pyruvate dehydrogenase. This enzyme catalyzes the reaction of pyruvate with coenzyme A to form acetyl CoA. This reaction is sometimes called the link reaction, as it links glycolysis to the Krebs cycle (= citric acid cycle, or tricarboxylic acid cycle).
"Pyruvate dehydrogenase" is in fact a huge complex (bigger than a ribosome) consisting of three enzymes and a number of other substances, including coenzymes. In the course of the reaction NAD+ is reduced to NADH. A molecule of CO2 is also produced. So this reaction involves a both an oxidation and a decarboxylation.
Acetyl CoA then reacts with oxaloacetate to form citrate. Both oxaloacetate and citrate are intermediates of the Krebs cycle.
What else can I help you with?
For glycolysis to begin glucose must enter the mitochondria?
Actually, glycolysis takes place in the cytoplasm of the cell, not the mitochondria. Glucose is broken down into pyruvate during glycolysis, and the pyruvate can then enter the mitochondria for further processing in the citric acid cycle and oxidative phosphorylation.
When does Calvin cycle begin?
When acetyl CoA and oxaloacetate is present.
Do pyruvate molecule which is the product of glycolysis enters the mitrochondria during cellular respiration?
Yes, pyruvate molecules produced during glycolysis enter the mitochondria where they undergo further chemical reactions in the citric acid cycle to generate energy in the form of ATP. This process occurs in the matrix of the mitochondria.
Where is pryuvate made in the cell?
Pyruvate is produced in the cell's cytoplasm during the process of glycolysis. Glycolysis breaks down glucose into pyruvate, which can then enter the mitochondria to undergo further energy production in the form of ATP through the citric acid cycle and oxidative phosphorylation.
How does galactose enter the Krebs cycle?
Galactose is converted to glucose-6-phosphate, which can enter glycolysis to produce pyruvate. Pyruvate can then be converted to acetyl-CoA, a molecule that enters the Krebs cycle. This allows galactose-derived metabolites to be utilized in the Krebs cycle for energy production.
For glycolysis to begin glucose must enter the mitochondria?
Actually, glycolysis takes place in the cytoplasm of the cell, not the mitochondria. Glucose is broken down into pyruvate during glycolysis, and the pyruvate can then enter the mitochondria for further processing in the citric acid cycle and oxidative phosphorylation.
When does Calvin cycle begin?
When acetyl CoA and oxaloacetate is present.
Do pyruvate molecule which is the product of glycolysis enters the mitrochondria during cellular respiration?
Yes, pyruvate molecules produced during glycolysis enter the mitochondria where they undergo further chemical reactions in the citric acid cycle to generate energy in the form of ATP. This process occurs in the matrix of the mitochondria.
Where is pryuvate made in the cell?
Pyruvate is produced in the cell's cytoplasm during the process of glycolysis. Glycolysis breaks down glucose into pyruvate, which can then enter the mitochondria to undergo further energy production in the form of ATP through the citric acid cycle and oxidative phosphorylation.
What happens to pyruvate molecules formed glycolysis in the absence of oxygen?
they will enter the Krebs cycle
What can you do with the end product of glycolysis?
The end product of glycolysis is pyruvate. Pyruvate can be further metabolized through aerobic respiration in the presence of oxygen, entering the citric acid cycle to generate more ATP. In the absence of oxygen, pyruvate can undergo fermentation to generate ATP anaerobically.
What is a product of aerobic respiration that will enter into and begin the Krebs cycle?
glycolysis yiels 2 pyruvate molecules that will undergo Kreb's cycle
How do redox environment of cell determine weither glycolysis is aerbic or anerobic?
Merely the presence of oxygen determines whether pyruvate will enter the citric acid cycle or be cycled in glycolysis to produce ATP.
How does galactose enter the Krebs cycle?
Galactose is converted to glucose-6-phosphate, which can enter glycolysis to produce pyruvate. Pyruvate can then be converted to acetyl-CoA, a molecule that enters the Krebs cycle. This allows galactose-derived metabolites to be utilized in the Krebs cycle for energy production.
Where the gloucse is broken down to produce pyrumate?
Glycolysis is the process in which glucose is broken down in the cytoplasm of cells to produce pyruvate. This series of reactions generates ATP, NADH, and pyruvate, which can then enter the citric acid cycle for further energy production.
When oxygen is present what porduct enters the second stage of cellular respiration?
When oxygen is present, pyruvate molecules produced in glycolysis enter the second stage of cellular respiration, which is the citric acid cycle (Krebs cycle). In this cycle, pyruvate is converted to acetyl CoA, which then enters the citric acid cycle to generate ATP through a series of redox reactions.
Why only glucose enters into glycolysis why not other sugars directly enter into glycolysis?
Other sugars do enter into glycolysis such as fructose, galactose and mannose. Fructose can directly enter into glycolysis while the other two is converted to a glucose intermediate molecule because it can produce the two triose phophate molecules (DHAP and G3P) which are needed to generate energy from the reactions (ATP) and pyruvate.
