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If there is an excess of Vitamin C in the body, then the kidneys must work to remove it from your blood and get rid of it as liquid waste.

However, this does not strain the kidneys nearly as much as taking most drugs would (except for those which strain the liver, instead), so you shouldn't have anything to worry about. Just use reasonable amounts (when you are not sick, 4 to 5 grams should be plenty - even 1-2 grams will probably be enough) and you should be fine.

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