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Epinephrine is controlled through a negative feedback system involving the hypothalamus, pituitary gland, and adrenal glands. When the body perceives stress or danger, the hypothalamus signals the pituitary gland to release adrenocorticotropic hormone, which in turn stimulates the adrenal glands to produce and release epinephrine. Once the epinephrine levels are sufficient to address the stressor, the negative feedback loop is activated to reduce further release.

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1y ago

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