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what to do look up the pK values for the different amino acids. identify R groups which have pKR values (ie can act as acis and bases) also locate the pK values for the N and C terminal groups as these contribute to charge determine if each group is either a proton donor or proton acceptor at pH 7 determine the charge on each group by looking at the structure take the sum of individual charge to obtain the net charge on the peptide what to do Look up the pK values for the different amino acids. Identify R groups which have pKR values (ie can act as acis and bases). Also locate the pK values for the N and C terminal groups as these contribute to charge. Next determine if each group is either a proton donor or proton acceptor at pH 7. Determine the charge on each group by looking at the structure. Finally take the sum of individual charge to obtain the net charge on the peptide. what to do Look up the pK values for the different amino acids. Identify R groups which have pKR values (ie can act as acis and bases). Also locate the pK values for the N and C terminal groups as these contribute to charge. Next determine if each group is either a proton donor or proton acceptor at pH 7. Determine the charge on each group by looking at the structure. Finally take the sum of individual charge to obtain the net charge on the peptide.

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How do you calculate the isoelectric point of a peptide?

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How can one determine the isoelectric point of a peptide?

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