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Yes it is. There are more triplet codons than there are [biologically active] amino acids that need to be represented in the Cell, so that there is some duplication of codon/amino acid 'alignment'. This occurs only in the third base position of the triplet codon - the 'wobble base' position - so if a mutation occurred in the wobble (third) position and the codon was one of the few that was not alone in its amino acid specificity this mutation would go unnoticed.

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