Down syndrome results from a nondisjunction during cell division. That is, homologous chromosomes 21 fail to separate in meiosis I, or sister chromatids 21 during meiosis II or mitosis.
Down syndrome is caused by trisomy of chromosome 21 (an extra chromosome to the usual two), which is an autosomal chromosome. Therefore it is not a sex linked disorder.
Sexlinked and recessive.
Cooley's anemia, also known as beta-thalassemia, is an autosomal recessive genetic disorder. This means that both copies of the gene must be mutated in order for the disease to be present. It is not a sex-linked trait.
Color blindness is a recessive trait, meaning that an individual needs to inherit two copies of the gene for color blindness (one from each parent) in order to be color blind. If an individual inherits only one copy of the gene, they are considered a carrier and will not exhibit color blindness.
No, thalassemia is a genetic blood disorder that affects the production of hemoglobin in red blood cells. Blood group and Rh factor are determined by different genetic markers and are not directly linked to thalassemia.
Sickle cell disease is an autosomal reccessive sexlinked trait so, a female msut have 2 recessive alleles to have the trait and a male needs only one allele (this is because there is no corresponding site for this allele on the Y chromosome. The female can be a carrier of the disorder with the defective allele on one X chromosome and a normal allele on the other X chromosome. Female carrriers can have a mixture of normal and abnormal redblood cells.
Sexlinked and recessive.
If you have beta thalassemia trait and your partner has sickle cell trait there is a 25% chance of your child having sickle beta thalassemia.
Yes, Thalassemia sex is a linked trait. Ha ;)
Nope! The disease is equally in both males and females. This means that it is autosomal.
have seen one of my friends sister had kid and all normal no complications...not thalassemia either.........beta and alpha i think there is 25% normal chance
It is unlikely.
you have a 50/50 chance me and my twin both had it and my 2 older brothers are fine 1 is a carrier and the other is not.
Thalassemia Intermedia is a recessive trait inherited disease of the red blood cells. In thalassemia, the genetic defect results in reduced rate of synthesis of normal hemoglobin chains.
Thalassemia itself does not prevent malaria, but individuals with thalassemia trait or certain forms of thalassemia may have a degree of protection against severe malaria due to the altered shape and function of their red blood cells. This change can make it more difficult for the malaria parasite to survive and reproduce. Consequently, while thalassemia does not prevent malaria infection, it can potentially reduce the severity of the disease in affected individuals.
i was told many years ago that i couldn't donate as I'm a beta thalassemia carrier. best to ask your local donation center.
If untreated, beta thalassemia major can lead to severe lethargy, paleness, and delays in growth and development. The body attempts to compensate by producing more blood, which is made inside the bones in the marrow.
This is a type of solubility testing for sickle cell disease. It is very specific for this disease and several combinations sickle cell / thalassemia variants but inadequate for screening and fail to identify important transmissible hemoglobin gene abnormalities - particularly in the prenatal setting when looking for those that affect fetal outcome (eg, Hb C trait, β-thalassemia trait, Hb E trait, Hb B trait, Hb D trait).