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There is a neurotoxin found in pufferfish, blue-ringed octopus, and in some other amphibians including newts, toads, and frogs called tetrodotoxin. See wikipedia for an exhaustive treatment of it's mechanism. Voodoo magicians in Haiti made this topic famous by using the toxin from a certain type of frog to induce a comatose-like state in a person. The person would be taken for dead, (and though still conscious) buried, and then exhumed by those who would use these brain-damaged people to work on sugar cane farms as slaves.

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