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The major skin area from which the derivatives arise is the stratum basale, which is the deepest layer of the epidermis. This layer contains stem cells that continuously divide and differentiate to give rise to the various cell types in the epidermis, including keratinocytes, melanocytes, and Merkel cells. These cells migrate upwards through the layers of the epidermis to replenish and repair the skin.

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1y ago

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