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Extravascular hemolysis occurs when degradation of rbc's by macrophages occur in the liver and spleen. The most common form of extravascular hemolysis occurs in hemolytic anemia.

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Where is rbc destroyed in human body?

Red blood cells (RBCs) are primarily destroyed in the spleen. The spleen is responsible for filtering and removing old or damaged RBCs from the bloodstream. Macrophages in the spleen engulf and break down these RBCs, recycling their components for future use.


What happens if rbc's and saline solutions are mixed?

If red blood cells (RBCs) are mixed with a saline solution, the RBCs may undergo hemolysis, where they rupture and release their contents into the solution. This can lead to changes in the osmotic balance and potentially cause damage to the RBCs. It is important to handle RBCs carefully to prevent hemolysis and maintain their function.


Why we can not extract DNA from RBCs?

We can not extract DNA from RBCs as they are without nucleus. only the source of DNA extraction is Leukocytes, RBCs are not good source of extraction but we can extract DNA from immature RBCs.


What system is spleen lymphatic tissuue?

Yes, it is lympahtci tissue but is recycles RBCs and stores many RBCs in case of a massive blood loss.


Where does the nucleus go in a red blood cell?

In mature red blood cells (RBCs), the nucleus is expelled during the process of erythropoiesis, which occurs in the bone marrow. This loss of the nucleus allows RBCs to maximize space for hemoglobin, the protein responsible for oxygen transport. As a result, mature red blood cells do not contain a nucleus, enabling them to be more flexible and efficient in their role within the circulatory system.

Related Questions

Where is rbc destroyed in human body?

Red blood cells (RBCs) are primarily destroyed in the spleen. The spleen is responsible for filtering and removing old or damaged RBCs from the bloodstream. Macrophages in the spleen engulf and break down these RBCs, recycling their components for future use.


How are red blood cells recycled?

Eventually the RBCs are unable to spring back into shape as they pass through capillaries and this lack of flexibility traps old RBCs in the spleen. The damaged RBCs are phagocytosed by macrophages, the proteins are hydrolyzed, iron is concentrated in transferrin and the chemical frame of the heme structure is partially disassembled and ultimately eliminated as part of the bile used in digestion. Millions of RBCs are born and recycled each day to maintain a constant level of oxygen in tissues .


Macrophages or phagocytes are inhibited by the increased amound of RBCs in the inflamed area T or F?

I'm pretty sure its false. I have it marked false on my hw and I think i found it in the chapter. Keep googling though just in case.


When a blood vessels are injured there are tiny blank in the blood that help the blood to clot and seal the cut?

The blood always has platelets, and RBCs have macrophages. Platelets help clot the blood. Macrophages start to clean up debris and any infection. The site of a cut becomes warm and slightly red because of the cellular activity being increased in the localized area.


Why shivering occurs in case of malaria until a person is suffering from high fever?

A person suffering from malaria has those parasites entering into his RBCs by breaking the cells.Since several parasites are involved in the invasion there is a greater destruction of the RBCs which produces shivering


How do antibodies kill the red blood cells?

Antibodies can lead to the destruction of red blood cells (RBCs) through a process known as opsonization and complement activation. When antibodies bind to antigens on the surface of RBCs, they mark these cells for destruction. This binding can activate the complement system, leading to the formation of membrane attack complexes that create pores in the RBC membrane, causing lysis. Additionally, phagocytic cells, like macrophages, can recognize and engulf the antibody-coated RBCs, ultimately leading to their removal from circulation.


What is the compatibility testing for agglutination of donor RBCs by the recipeints' serum?

Compatibility testing involves mixing donor red blood cells (RBCs) with recipient serum to check for agglutination. If agglutination occurs, it indicates incompatibility between the donor RBCs and recipient serum, suggesting a mismatch that could lead to a transfusion reaction. Testing is crucial to ensure safe blood transfusions.


Which cells in your body can change their shape?

Cells in your body that can change their shape include red blood cells, white blood cells (such as neutrophils and macrophages), and muscle cells (such as muscle fibers). These cells have the ability to alter their shape to carry out their specific functions.


Why are rbcs short lived?

Red blood cells (RBCs) are short-lived, typically around 120 days, due to their lack of nuclei and organelles, which limits their ability to repair and regenerate. As they age, they accumulate damage from oxidative stress and mechanical wear from circulation. Additionally, their primary function is to transport oxygen and carbon dioxide, which creates wear on their membranes. Eventually, they are removed from circulation by the spleen and liver, where macrophages recycle their components.


What is the significance of Enumerated?

low rbcs count shows anaemia high rbcs count show polycythemia vera. rbcs enumerations shows the bonemarrow how much active.


Why spleen called graveyard of rbc?

The spleen is often referred to as the "graveyard" of red blood cells (RBCs) because it plays a crucial role in filtering and recycling old or damaged RBCs from the bloodstream. As blood passes through the spleen, macrophages engulf and break down these cells, allowing the iron and other components to be reused for the production of new blood cells. This process helps maintain healthy blood cell levels and ensures the removal of ineffective or worn-out cells.


Where are the rbc's made?

Red blood cells (RBCs) are primarily produced in the bone marrow, a spongy tissue found in the center of certain bones. In adults, this process mainly occurs in the vertebrae, ribs, sternum, and pelvis. The production of RBCs, known as erythropoiesis, is stimulated by the hormone erythropoietin, which is produced by the kidneys in response to low oxygen levels in the blood.