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Are centrioles required for microtubule assembly and disassembly?
Centrioles are important for organizing microtubules within the cell, but they are not directly involved in microtubule assembly or disassembly. However, centrioles play a role in nucleating the assembly of microtubules in certain cellular processes.
What is assembly of microtubules?
Assembly of microtubules is the process by which tubulin proteins polymerize to form a hollow tube structure. This process is highly regulated and essential for various cellular functions, including cell division, intracellular transport, and cell shape maintenance. Microtubules are a critical component of the cytoskeleton in eukaryotic cells.
The mitotic spindle formation depends upon?
The formation of the mitotic spindle depends upon the proper assembly and organization of microtubules, which are dynamic protein fibers that make up the spindle apparatus. Microtubules are regulated by microtubule-associated proteins that help facilitate their polymerization and depolymerization processes. Additionally, motor proteins are essential for moving the chromosomes to their correct positions during mitosis.
What is the complex assembly of micro-tubules that occur in pairs?
The complex assembly of microtubules that occurs in pairs is known as a "doublet." These doublets are primarily found in structures like cilia and flagella, where they play a crucial role in cellular movement. In these structures, nine pairs of microtubules are arranged in a circular pattern, with two additional microtubules in the center, forming a characteristic "9+2" arrangement. This configuration is essential for the motility and functionality of these organelles.
In what stages of mitosis would you expect to find mostly polymerization taking place?
During mitosis, polymerization of microtubules primarily occurs in prophase and metaphase. In prophase, the mitotic spindle begins to form as microtubules polymerize, extending from the centrosomes. This process continues in metaphase, where the spindle fibers attach to the chromosomes at the kinetochores, facilitating their alignment at the cell's equatorial plane. Overall, these stages are characterized by significant microtubule assembly as the cell prepares for chromosome separation.
Does an internal regulatory protein prevent cell from entering anaphase if chromosomes have not attached to spindle fibers?
Yes, an internal regulatory protein called the spindle assembly checkpoint (SAC) monitors the attachment of chromosomes to spindle fibers. If chromosomes are not correctly attached, the SAC delays progression to anaphase by inhibiting the activity of the anaphase-promoting complex (APC) until all chromosomes are properly aligned. This ensures accurate segregation of chromosomes during cell division.
Are centrioles required for microtubule assembly and disassembly?
Centrioles are important for organizing microtubules within the cell, but they are not directly involved in microtubule assembly or disassembly. However, centrioles play a role in nucleating the assembly of microtubules in certain cellular processes.
What is a function of those spindle microtubules that do not attach to kinetochores?
microtubules attached to a chromosome Wiki Answers respondents need to start answering questions with a greater sense of purpose. People do not ask questions to receive a terse, slightly correct answer. They want a valid answer to a valid question. As per this one, kinetochore microtubules are NOT just microtubules attached to a chromosome. They are microtubules attached to kinetochores on the centromeres of chromatids. Two chromatids make up a "chromosome" and each chromatid has a centromere with a kinetochore on it. When microtubules from the spindle pole attach to the kinetochores on each side of the "chromosome" the two kinetochore microtubules (from opposite poles of the cell) successfully pull the "chromosome" apart and provide each new developing daughter cell nucleus with a chromatid from that chromatid pair.
What is assembly of microtubules?
Assembly of microtubules is the process by which tubulin proteins polymerize to form a hollow tube structure. This process is highly regulated and essential for various cellular functions, including cell division, intracellular transport, and cell shape maintenance. Microtubules are a critical component of the cytoskeleton in eukaryotic cells.
The cancer drug vinblastine interferes with synthesis of microtubules and in mitosis this would interfere with what?
Vinblastine interferes with the synthesis of microtubules, which are essential for the formation of the mitotic spindle during cell division. This interference can disrupt the proper alignment and segregation of chromosomes during mitosis, leading to cell death or inhibition of cell proliferation.
How are centrioles involved in the formation and organization of microtubules within the cell?
Centrioles are involved in the formation and organization of microtubules within the cell by serving as the main organizing centers for the assembly of microtubules. They help to nucleate and anchor the microtubules, which are essential for various cellular processes such as cell division and intracellular transport.
The mitotic spindle formation depends upon?
The formation of the mitotic spindle depends upon the proper assembly and organization of microtubules, which are dynamic protein fibers that make up the spindle apparatus. Microtubules are regulated by microtubule-associated proteins that help facilitate their polymerization and depolymerization processes. Additionally, motor proteins are essential for moving the chromosomes to their correct positions during mitosis.
In animal cells microtubules grow from which structure?
Microtubules grow from the microtubule-organizing center (MTOC), which is typically located near the cell nucleus. The MTOC serves as a major organizing site for the assembly of microtubules, providing the necessary environment for their formation and growth.
What are hollow tubes made of spherical protein subunits called tubulins?
Hollow tubes made of spherical protein subunits called tubulins are known as microtubules. These microtubules play a crucial role in cell structure, cell division, intracellular transport, and cellular movement in all eukaryotic cells. The dynamic assembly and disassembly of microtubules are tightly regulated in the cell.
When are centioles used?
Centrioles are used when cells divide. They are found in animal cells and organize the assembly of microtubules during division.
How does the structure of microtubules allow them to apparently move from one location of a cell to another?
Microtubules are made of a dimer protein called tubulin. They grow in length by adding tubulin dimers, but they can also be disassembled. This process of assembly and disassembly makes the microtubule seem to move from one location of the cell to another.
What do a assembly line do?
The assembly-line manager or supervisor is only responsible for the line that he or she oversees
