Nocturnal myoclonus-- A disorder in which the patient is awakened repeatedly during the night by cramps or twitches in the calf muscles. Nocturnal myoclonus is sometimes called periodic limb movement disorder (PLMD).
Nocturnal myoclonus, also known as nocturnal leg cramps, are characterized by sudden, involuntary contractions of leg muscles during sleep. Symptoms include intense pain, muscle tightening, and visible lumps or knots in the affected muscle. The cramps usually occur in the calf muscles and can lead to disrupted sleep.
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One can suffocate when there is insufficient supply of oxygen to the body. This can occur under water, in chemical contaminated areas, pollution of air with excessive carbon monoxide or nitrogen. Suffocation can also occur when a person gets buried under heavy load or gets trapped under sand.
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Rarely, opsoclonus myoclonus can occur after the use of certain medications such as intravenous phenytoin or diazepam , or subsequent to an overdose of the antidepressant amitriptyline
Most children who develop opsoclonus myoclonus are under the age of two when they are diagnosed.
Nocturnal myoclonus
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Treatment of the symptoms of opsoclonus myoclonus include clonzaepam or valproate. These may decrease the severity of both the opsoclonus and the myoclonus.
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Diagnosis is primarily arrived at through identification of concurrent opsoclonus and myoclonus.
Treatment of myoclonus is rarely entirely successful. The patient is likely to have some residual myoclonus even with the most successful treatments. Nonetheless, treatment may reduce frequency and severity
Evolution would not occur if there is no genetic variation within a population, no selection pressure, or if there is no reproduction and passing on of genes to the next generation.
Myoclonus describes the sudden involuntary jerking of a muscle.Nocturnal myoclonus
In children, the most common type of tumor that precipitates opsoclonus myoclonus is called neuroblastoma.
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