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Cell cycle regulators, often referred to as cyclins and cyclin-dependent kinases (CDKs), can originate from various sources. Three key sources include: 1) Cellular transcription where genes encoding these proteins are expressed; 2) Post-translational modifications that can activate or inhibit these regulators; and 3) Extracellular signals, such as growth factors, that can influence the expression and activity of these cell cycle proteins.

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