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Hemodynamic signals, the basis of functionality for the fMRI (functional Magnetic Resonance Imaging) involve detecting the difference between oxygenated and deoxygenated hemoglobin (Blood with or without oxygen). Increasing neural activity causes a need for more oxygen, which increases the appearance of oxygenated hemoglobin around that specific neuron. Hemodynamic signals are used to detect active areas in the brain relative to inactive areas.

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