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A sense mutation happens among the bases that code for actual amino acids: The sense. One variation here could be disastrous, or five could be a beneficial mutation.

Sickle cell trait varies bu only one amino acid on the B protein of hemoglobin and can be life threatening in homozygous condition, or beneficial in heterozygous condition.

Most mutations fall among the non-sense portions of the genome and are neutral.

And now the Techno Fun Portion: the anti sense [non-sense] mutation is Stdby::

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