Pharmaceuticl suspensions are solid dipersion of insoluble or sparingly-soluble drugs, in aqueous or oily vehicles. They are intended for oral administration, topical application or parenteral administration of drugs.
Aerosol suspension of finely divided, or micronized drugs, is also another class of pharmaceutical preparations intended for inhalation.
Suspension of drugs for oral administration is an easy way to administer insoluble, or sparingly soluble, drugs to infants and eldery who have difficulty in administering drugs in tablet or capsule forms. Also for rapid absorption of some insoluble drugs, which are slowly absorbed from tablet dosage form, such as griseofulvin, prepared in suspensions form of the micronized drug.
The insoluble basic drug, or the insoluble salt or compound of a drug, is frequently used rather than using the soluble salt, to retard absorption of the drug. This is used for the preparation of prolonged released dosage forms to avoid frequent administration of the drug.
Sometimes insoluble salts or compounds of the dugs are used to avoid the bitter taste of the soluble form; for example the use of chloramphenicol palmitate in suspension, instead of using the very bitter soluble chloramphenicol.
Some eye drops or ear drops are also prepared in suspension form for drugs which are sparingly soluble, or intenetially using the insoluble form to prolong the time of action of the drug, such as corticosteroid preparations. Samir M. Bayoumi
Prof. of Pharmaceutics
samir.bayoumi@mcphs.edu
Some examples of animal cell suspension culture include the growth of Chinese hamster ovary (CHO) cells, mouse myeloma cells, and human embryonic kidney (HEK) cells in suspension in a nutrient-rich medium. These cultures are commonly used in biotechnology and pharmaceutical research for protein production and cell-based assays.
In a pharmaceutical suspension, a suspending agent helps the drug stay in the body of your suspension thereby preventing caking at the bottom. One of the properties of a well-formulated suspension is that it can be easily resuspended by the use of moderate agitation.
A mixture that contains undissolved solids is known as a suspension. In a suspension, solid particles are dispersed throughout a liquid but do not dissolve, resulting in a cloudy appearance. Common examples include muddy water, where soil particles are suspended, and certain pharmaceutical preparations, like some liquid medications that contain solid ingredients. Over time, the solid particles in a suspension may settle to the bottom if left undisturbed.
1. any sediment (solid material) which accumulates when stored is readily dispersed. 2. After gently shaking, the medicine stays in suspension long enough for a dose to be accurately measured 3. The suspension is pourable
A suspension is a heterogeneous mixture where solid particles are suspended in a liquid. Food examples include salad dressings, certain types of sauces, and some beverages where particles do not dissolve but remain suspended in the liquid.
Some examples of animal cell suspension culture include the growth of Chinese hamster ovary (CHO) cells, mouse myeloma cells, and human embryonic kidney (HEK) cells in suspension in a nutrient-rich medium. These cultures are commonly used in biotechnology and pharmaceutical research for protein production and cell-based assays.
In a pharmaceutical suspension, a suspending agent helps the drug stay in the body of your suspension thereby preventing caking at the bottom. One of the properties of a well-formulated suspension is that it can be easily resuspended by the use of moderate agitation.
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sodium acetate tyihydrate
There are 2 awesome examples of suspension in the human body. The knees and the spine. The spine will contract slightly and act as suspension when jumping and walking. The knees acts as suspension as well.
syrup is a pharmaceutical solution that completely dissolves into its solvent, with the distribution of drugs within the solution being even, a suspension is drug mixture whereby the drug particles do not fully dissolve into the solvent.
Orange juice, pond water, and Italian salad dressing are examples of liquid heterogeneous mixtures.
Pharmaceutical research
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it means developing area of any dosage form like tablet,capsule,syrup,suspension etc. in this laboratories they get the active ingredients and excepients from different suppliers and develops the new products this is called pharmaceutical manufacturing laboratories................
1. any sediment (solid material) which accumulates when stored is readily dispersed. 2. After gently shaking, the medicine stays in suspension long enough for a dose to be accurately measured 3. The suspension is pourable
Examples: pharmaceutical products, foods additives, materials for electronics or optics etc.