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The factors which affect LCST include the hydrophobi and hydrophilic compositions. For example, PNVCL ( Poly(N-Vinyl caprolactam) has got LCST in the range of 32Degree Celcious, which can be modified by incorporating more hydrophobic moeities in to it. The more hydrophylic the polymer, less would be its LCST and vice versa.

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