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In the final stages of myelofibrosis, the bone marrow becomes extensively scarred, leading to severe cytopenias (low blood cell counts), increased risk of infections and bleeding, enlargement of the spleen and liver, and progressive symptoms such as fatigue, weight loss, and pain. Patients may also develop complications such as acute leukemia or transformation to myelodysplastic syndrome.
What else can I help you with?
The final phase of mitosis is-?
The final phase of mitosis is called Telophase. The other stages are Prophase, Metaphase and Anaphase.
What are the three stages of quarrying?
The three stages of quarrying are extraction of the material from the ground or rock face, processing the extracted material to separate the desired product from waste material, and transporting the final product to end-users or storage facilities.
Can anemia cause tear drop shaped red blood cell?
Yes, anemia can cause the production of tear drop-shaped red blood cells. This abnormal shape is associated with conditions like myelofibrosis, where the bone marrow is replaced by fibrous tissue. Anemia in myelofibrosis can lead to the release of immature red blood cells that can have abnormal shapes.
What are the 9 stages of a human's life?
There are nine stages of a human's life. Infancy, early childhood, childhood, adolescence, young adulthood, first adulthood, second adulthood, and final adulthood are the stages that most people go through in the course of their life.
What are the stages of purchasing?
The stages of purchasing typically include awareness, consideration, decision, and post-purchase evaluation. During awareness, the consumer identifies a need or want. In the consideration stage, they research and evaluate options. The decision stage involves making the final purchase, and post-purchase evaluation assesses satisfaction and potential repeat purchases.
Can Myelofibrosis get worse?
Myelofibrosis can progress to acute lymphocytic leukemia or lymphoma
What are other names for Myelofibrosis?
Myelofibrosis goes by many names including idiopathic myelofibrosis, agnogenic myeloid metaplasia, chronic myelosclerosis, aleukemic megakaryocytic myelosis, and leukoerythroblastosis
What does Myelofibrosis stem from?
Myelofibrosis is caused by an abnormality in a single stem cell, which causes it to grow out of control
Is idiopathic myelofibrosis fatal?
Idiopathic myelofibrosis typically becomes progressively worse and can cause death
Does myelofibrosis always produce symptoms?
About one quarter of all patients with myelofibrosis have no symptoms (asymptomatic)
Is myelofibrosis easy to diagnose?
Because symptoms are similar to other diseases (mostly leukemias), myelofibrosis is not easy to diagnose
Does Bone marrow transplantation treat myelofibrosis?
Although historically there has not been much improvement in the treatment of myelofibrosis, that has changed recently. The main treatment now consists of taking a medication known as "Jakafi" which targets the gene thought to cause myelofibrosis.
Is fatigue a symptom of myelofibrosis?
Yes
Is fever a symptom of myelofibrosis?
Yes
Is itchiness a symptom of myelofibrosis?
Yes
Is Myelofibrosis associated with leukoerythroblastosis?
Yes
Is Myelofibrosis associated with tuberculosis?
Yes
