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The four stages of macromolecules refer to the levels of structure that proteins, nucleic acids, carbohydrates, and lipids can assume. These stages are primary (the linear sequence of monomers), secondary (local folding patterns like alpha helices and beta sheets), tertiary (the overall three-dimensional shape), and quaternary (the assembly of multiple polypeptide chains into a functional unit). Each stage is crucial for the macromolecule's function and biological role.

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