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· Hormonal stimuli - the most common; endocrine organs are prodded into action by other hormones. Hormone release promoted by this mechanism tends to be rhythmic, with hormone blood levels rising and falling again and again

· Humoral Stimuli - changing blood levels of certain ions and nutrients stimulate hormone release. Humoral refers to humor to indicate the various body fluids (blood, bile, etc).

· Neural Stimuli - In isolated cases, nerve fibers stimulate hormone release, and the target cells are said to respond to neural stimulus. The classic example is sympathetic nervous system stimulation of the adrenal medulla to release norepinephrine and epinephrine during periods of stress.

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