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Crystals can form under the skin due to conditions like gout or calcium pyrophosphate deposition disease. In gout, high levels of uric acid in the blood can lead to the formation of urate crystals in joints and surrounding tissues. In calcium pyrophosphate deposition disease, crystals of calcium pyrophosphate can accumulate in joints, causing pain and inflammation.

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1y ago

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The build-up of salt crystals under the skin, known as pseudogout, is typically caused by the deposition of calcium pyrophosphate dihydrate crystals. These crystals form due to an abnormal accumulation of calcium in the joints, leading to inflammation, pain, and swelling. Factors such as aging, genetics, and underlying medical conditions can contribute to the development of pseudogout.


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