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The cells most involved in thermoregulation are thermoreceptors, which are specialized sensory neurons located in the skin and the hypothalamus. These receptors detect changes in temperature and send signals to the hypothalamus, the body's temperature regulation center. Additionally, effectors such as sweat glands and blood vessels, which are controlled by the autonomic nervous system, play crucial roles in heat dissipation and conservation. Ultimately, this coordinated response helps maintain homeostasis in body temperature.

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