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During the prophase stage of mitosis, the nuclear envelope disappears, and the nucleolus fades from view. The chromatin condenses into visible chromosomes, which consist of two sister chromatids joined at the centromere. As mitosis progresses into metaphase, the spindle fibers emerge, attaching to the centromeres of the chromosomes. The nuclear envelope will reappear in the later stages of mitosis, specifically during telophase.

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6d ago

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