A mutation in the CFTR gene causes the protein CFTR to fold improperly. This mutation results in a defective CFTR protein that cannot function properly, leading to the development of cystic fibrosis.
The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane regulator.
The amino acid missing in the CFTR protein in people with cystic fibrosis is phenylalanine at position 508, resulting from a deletion of a single codon (ΔF508). This deletion leads to improper folding and trafficking of the CFTR protein, causing it to be degraded and non-functional.
Its name is CFTR and is a membrane channel for chlorine ions. Genetic defects in CFTR brings to an increased concentration of chlorine ions that lead to a greater viscosity of mucus in several mucosae in lungs and pancreas.
Cystic fibrosis is caused by defective CFTR protein. CFTR is an ion channel that transports chloride ions across epithelial cell membranes.
Cystic fibrosis is primarily caused by mutations in the CFTR gene, which is located on chromosome 7. These mutations can result in a defective or non-functioning CFTR protein, leading to the characteristic symptoms of the disease.
fold improperly
fold improperly
The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane regulator.
The amino acid missing in the CFTR protein in people with cystic fibrosis is phenylalanine at position 508, resulting from a deletion of a single codon (ΔF508). This deletion leads to improper folding and trafficking of the CFTR protein, causing it to be degraded and non-functional.
Yes, it is caused by a mutation in the gene for the protein CFTR.
Its name is CFTR and is a membrane channel for chlorine ions. Genetic defects in CFTR brings to an increased concentration of chlorine ions that lead to a greater viscosity of mucus in several mucosae in lungs and pancreas.
Cystic fibrosis is caused by defective CFTR protein. CFTR is an ion channel that transports chloride ions across epithelial cell membranes.
Cystic fibrosis is primarily caused by mutations in the CFTR gene, which is located on chromosome 7. These mutations can result in a defective or non-functioning CFTR protein, leading to the characteristic symptoms of the disease.
No, cystic fibrosis is caused by mutations in the CFTR gene, not by the presence of extra chromosomes. Individuals with cystic fibrosis inherit two faulty copies of the CFTR gene, one from each parent, which leads to the production of a defective CFTR protein that affects the movement of salt and water in and out of cells.
Cystic Fibrosis is caused by the gene which codes for the protein CFTR--Cystic Fibrosis Transmembrane Conductance Regulator, which is found on chromosome 7. The protein transports chloride ions across epithelial cell membranes.
The CFTR protein regulates the flow of chloride ions in and out of cells, helping to maintain the balance of salt and water in various tissues, including the lungs and digestive system. Its dysfunction can lead to cystic fibrosis, a genetic disorder affecting these systems.
The CFTR protein product is responsible for transporting chloride ions across epithelial cell membranes, which is crucial for maintaining the balance of salt and water in tissues. This function is essential for the proper functioning of organs such as the lungs, pancreas, and intestines. Mutations in the CFTR gene lead to cystic fibrosis, a condition characterized by thick mucus buildup and various complications in these organs. Overall, CFTR plays a vital role in fluid secretion and homeostasis in various bodily systems.