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Having an elevated C3 and C4 complement levels may suggest inflammation or activation of the immune system. It can be seen in conditions such as autoimmune diseases, infections, or certain cancers. Further evaluation by a healthcare provider is important to determine the underlying cause.

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What is C3 convertase?

Humans have both an "innate" and an "adaptive" immune system. There are a number of proteins circulating in the blood as part of the complement system that belongs to the innate immune system (although the adaptive system can activate it as well). Normally, the complement proteins are inactive. When the immune system detects some threat, the complement system is triggered and the circulating proteins are chemically split into smaller components. C3 convertases are chemicals that cleave C3 complement into breakdown products in both the "classical" and the "alternative" pathways of the complement system.


Which complement protein is the key to activating the alternative pathway of complement activation?

Factor B is the key complement protein that helps activate the alternative pathway of complement activation. It forms a complex with Factor D and is cleaved by Factor D to produce the active fragment, which leads to further activation of the alternative pathway.


What would be the likely outcome if a microbe could prevent the activation of C3 in the complement cascade?

If a microbe can prevent the activation of C3 in the complement cascade, it would likely evade the host immune response and avoid being targeted for destruction. This evasion strategy could help the microbe establish infection and cause disease without being effectively eliminated by the immune system.


How does membrane cofactor protein stop complement activation?

Membrane cofactor protein (MCP) acts as a cofactor for Factor I, which degrades C3b and C4b proteins, thus preventing the amplification of complement activation. By accelerating the decay of C3 convertases, MCP helps regulate the complement system and protect host cells from excessive complement-mediated damage.


How do i add cell c3 to c8 on an excel formular bar?

You would use the formula: =C3+C8 unless you mean to add everything from C3 to C8. IN that case you would use the formula =SUM(C3:C8)


In addition to IgC the antibodies that can fix complement are?

IgG and IgM can fix complement by activating the C3 protein at the end of the complement cascade allowing ADCC (antibody dependent cell- mediated cytoxicity) to occur. I have never heard of an IgC antibody. In humans there are only 5 classes of antibodies: IgM, IgG, IgA. IgD & IgE.


What does the medical abbreviation C3 mean?

The third cervical vertebra.


What is 6308 2RS1 C3 mean in bearing?

2RS Mean 2 Rubber Seal


How fast does a C7 shoot?

Do you mean the tippmann c3 propane gun.


What is 39 equals c3?

You mean: 39=3c 13=c


Is an apple a c3 or c4 plant?

An apple tree is a C3 plant, which means it uses the C3 photosynthetic pathway.


What might happen to someone whose body did not produce C3?

Individuals whose body do not produce C3, a key component of the complement system, can have an impaired immune response to infections. This can lead to an increased susceptibility to bacterial infections, particularly in the respiratory tract and bloodstream. These individuals may also experience recurrent infections and inflammation.