Oxaloacetate is a crucial component of the Krebs cycle as it combines with acetyl-CoA to form citrate, the first step in the cycle. It also regenerates at the end of the cycle to continue the process. Oxaloacetate plays a key role in the conversion of nutrients into energy in the form of ATP.
Acetyle Co-A + Oxaloacetate
Oxaloacetate is regenerated at the end of the cycle.
Fumarate and aspartate are the compounds that are linked between the urea cycle and the Krebs cycle. Fumarate from the Krebs cycle can be converted to arginine in the urea cycle, while aspartate from the urea cycle can be converted to oxaloacetate in the Krebs cycle.
citrate
Acetyl CoA (acetyl group) is the compound that enters the Kreb Cycle.
Oxaloacetate
Oxaloacetate
Oxaloacetate is an intermedier in the Krebs cycle
Acetyle Co-A + Oxaloacetate
Oxaloacetate is regenerated at the end of the cycle.
The starting molecule for the Krebs cycle is acetyl-CoA, which enters the cycle by combining with oxaloacetate to form citrate.
Carbon dioxide is recycled from the Krebs cycle in the form of the molecule oxaloacetate. This oxaloacetate can be used as a starting material to combine with acetyl-CoA to continue the cycle.
Fumarate and aspartate are the compounds that are linked between the urea cycle and the Krebs cycle. Fumarate from the Krebs cycle can be converted to arginine in the urea cycle, while aspartate from the urea cycle can be converted to oxaloacetate in the Krebs cycle.
The Krebs cycle starts with acetyl CoA, and combines with oxaloacetate to form citrate, a six-carbon molecule. Citrate is further oxidized until oxaloacetate is again reached at the end to restart the Krebs cycle.
citrate
An immediate consequence of a cellular deficiency of oxaloacetate is a slowing of the citric acid cycle (Krebs cycle). This cycle requires oxaloacetate to combine with acetyl-CoA to generate citrate, so a shortage of oxaloacetate can hinder this process, leading to reduced production of ATP through oxidative phosphorylation.
Acetyl CoA (acetyl group) is the compound that enters the Kreb Cycle.