Increased airway resistance leads to increased negative intra-pleural pressure (more negative pressure), as it requires increased effort to overcome the resistance and maintain adequate airflow into the lungs. This increased pressure difference helps to keep the airways patent by promoting dilation of the bronchioles. If the resistance becomes too high, it can result in excessive negative pressure and potentially lead to airway collapse.
High pressure alarm on a ventilator can be caused by factors such as kinked tubing, secretions blocking the airway, patient coughing or biting on the endotracheal tube, or increased resistance in the airway due to bronchospasm. It can also be triggered by the ventilator delivering too much volume or pressure to the patient.
The diameter of the airway is the most important factor in determining airway resistance. A smaller diameter increases resistance, making it harder for air to flow. Factors such as mucus, inflammation, and constriction can also affect airway resistance.
If compliance decreases, the mean airway pressure typically increases for a given tidal volume. This is because the lungs become stiffer, requiring greater pressure to achieve the same volume of air during inhalation. Consequently, the increased pressure can lead to higher mean airway pressures in mechanically ventilated patients.
Increased peak airway pressure in intubated patients may indicate decreased lung compliance, bronchospasm, or airway obstruction. It is crucial to assess and address the underlying cause promptly to prevent barotrauma and ensure adequate ventilation. Adjusting ventilator settings, assessing for proper endotracheal tube placement, and conducting a thorough clinical evaluation can help identify and manage the issue.
The nose, pharynx, and trachea are the parts of the upper airway. The tubes of the lungs comprise the lower airway.
Equal pressure point (EPP) is the point where Intrapleural pressure and Alveolar pressure are equal. This is similar to the Starling resistor concept in the lung. Instead of flow being determined by the difference between alveolar and mouth pressure- flow is determined by the difference between alveolar and Intrapleural pressure difference. In forced expiration, both intrapleural pressure and alveolar pressure will increase. However alveolar pressure will decrease along the length of the airway until a pressure of zero at the mouth, whereas intrapleural pressure will remain the same. Therefore there will be a point where intrapleural pressure will be equal and subsequently greater than alveolar pressure. If the EPP occurs in the larger cartilaginous airways, the airway remains open. However, if the EPP is in the smaller airways, it will collapse. Increasing the force of expiration does not overcome EPP since it will increase both alveolar and intrapleural pressure. Another interesting concept is that EPP moves distally as expiration progresses because as air leaves the alveolar unit, the pressure in the alveolar decreases hence the pressure in the airway decreases as well. EPP is the cause of dynamic airway compression.
Airway resistance refers to the obstruction or restriction of airflow in the respiratory passages. Increased airway resistance makes it harder for air to flow in and out of the lungs, requiring more effort and energy during breathing. This results in an increased work of breathing as the respiratory muscles have to work harder to overcome the resistance and maintain adequate ventilation.
High pressure alarm on a ventilator can be caused by factors such as kinked tubing, secretions blocking the airway, patient coughing or biting on the endotracheal tube, or increased resistance in the airway due to bronchospasm. It can also be triggered by the ventilator delivering too much volume or pressure to the patient.
The diameter of the airway is the most important factor in determining airway resistance. A smaller diameter increases resistance, making it harder for air to flow. Factors such as mucus, inflammation, and constriction can also affect airway resistance.
If compliance decreases, the mean airway pressure typically increases for a given tidal volume. This is because the lungs become stiffer, requiring greater pressure to achieve the same volume of air during inhalation. Consequently, the increased pressure can lead to higher mean airway pressures in mechanically ventilated patients.
airway length - a large surface area means more friction airway radius - halving the radius increases resistance 16-fold flow rate
Increased peak airway pressure in intubated patients may indicate decreased lung compliance, bronchospasm, or airway obstruction. It is crucial to assess and address the underlying cause promptly to prevent barotrauma and ensure adequate ventilation. Adjusting ventilator settings, assessing for proper endotracheal tube placement, and conducting a thorough clinical evaluation can help identify and manage the issue.
Increased airway resistance and reduced elastic recoil. Causes severe early dyspnea, scanty sputum, and hyperinflation.
cmH2O stands for centimeters of water, and is a unit of pressure used in medical settings to measure pressure exerted by mechanical ventilators during breathing. It indicates the pressure required to support or overcome the resistance of the patient's airway.
Continuous positive airway pressure (CPAP)-- A ventilation device that blows a gentle stream of air into the nose during sleep to keep the airway open.
CPAP-Continuous Positive Airway Pressure, SiPAP-Synchronized inspiratory Positive Airway Pressure
CPAP devices are masks that fit over the nose during sleep and deliver air into the airway under enough pressure to keep the airway open.