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Oligomycin inhibits ATP synthase in mitochondria, blocking oxidative phosphorylation, which is the process that generates ATP. This results in a decrease in ATP production, leading to a shift in cellular metabolism towards glycolysis and increased dependence on anaerobic respiration for energy production.

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1y ago

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ATP synthase can be inhibited exclusively by?

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Aerobic metabolism can be blocked by substances that interfere with the electron transport chain, such as cyanide, which inhibits cytochrome c oxidase. This prevents the transfer of electrons to oxygen, halting ATP production. Additionally, compounds like oligomycin can inhibit ATP synthase, blocking the synthesis of ATP from ADP and inorganic phosphate. As a result, the cell's ability to produce energy efficiently is compromised.


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