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If the re-uptake transporter is blocked, neurotransmitters remain in the synaptic cleft for a longer period, leading to prolonged stimulation of the postsynaptic receptors. This can enhance neurotransmission and potentially result in increased mood or altered perceptions, which is the basis for certain antidepressant medications. However, excessive neurotransmitter activity can also lead to adverse effects, such as anxiety or increased heart rate. Overall, blocking re-uptake transporters can significantly impact neural communication and overall brain function.

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4w ago

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