They are turned into acetyl Co-A. Then enters into Kreb cycle
Acetyl CoA forms.
Acetyl CoA forms.
Pyruvate is converted into acetyl CoA in the mitochondrial matrix through a series of enzymatic reactions known as the pyruvate dehydrogenase complex. Acetyl CoA then enters the citric acid cycle to produce energy in the form of ATP through a series of oxidation-reduction reactions.
If an electron acceptor is absent, pyruvate undergoes fermentation, resulting in the production of lactate in animals or ethanol and carbon dioxide in yeast, allowing for the regeneration of NAD+ and enabling glycolysis to continue. In contrast, if an electron acceptor is present, pyruvate enters the mitochondria and is oxidized in the citric acid cycle (Krebs cycle), leading to the production of ATP, NADH, and FADH2 through aerobic respiration. This process is more efficient in energy production compared to fermentation.
Acetyl CoA forms.
Acetyl CoA forms.
Acytle-CoA Forms.
Acetyl CoA forms.
Pyruvate is converted into acetyl CoA in the mitochondrial matrix through a series of enzymatic reactions known as the pyruvate dehydrogenase complex. Acetyl CoA then enters the citric acid cycle to produce energy in the form of ATP through a series of oxidation-reduction reactions.
Acetyl CoA forms.
glucose is changed into pyruvate
glucose is changed into pyruvate
One of the three carbon atoms that make up pyruvate is cleaved off by the rather large enzyme pyruvate dehydrogenase. This carbon atom attached to oxygen and becomes carbon dioxide(what you exhale). This reaction is known as a decarboxylation reaction. Then the other two remaining carbon atoms make up an acetyl group. Along with the acetyl group is hydrogen which will reduce NAD+ to NADH. The acetyl group is added to coenzyme a, and is called acetyl coenzyme a, or acetyl CoA for short. This is the ultimate creation of the oxidation of pyruvate. If there is a high concentration of ATP then the acetyl-CoA is used for fatty acid biosynthesis. If not than it will be used for oxidative metabolism. That's the basics of it for it is very complex.
In humans, under ANAEROBIC conditions (no O2), pyruvate is 'converted' to lactate, though I wouldn't say it is "broken down".In humans, under AEROBIC conditions (O2 present), pyruvate is converted to Acetyl-CoA, via the pyruvate dehydrogenase reaction.In yeast, pyruvate is converted into ethanol (Party Fluid) via pyruvate decarboxylase and then alcohol dehydrogenase.
The lactate is taken to the liver and converted back to pyruvate.
they will enter the Krebs cycle
Pyruvate is produced by glucose.By released enegy ATP and NADH is produced.