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When flagpole hydrogens in cyclohexane are replaced with methyl (CH₃) groups, the molecule's structure becomes a methyl-substituted cyclohexane, such as 1,2-dimethylcyclohexane. This substitution can lead to steric interactions and strain, particularly in chair conformations, where the axial methyl groups can create 1,3-diaxial interactions, increasing the overall energy of the molecule. The stability of the resulting conformers will depend on the positioning of the methyl groups, favoring equatorial positions to minimize steric hindrance.

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1mo ago

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