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When plasma osmolarity is not maintained within normal limits, it can lead to either hyperosmolarity or hypoosmolarity. Hyperosmolarity can cause cellular dehydration, leading to symptoms such as confusion, lethargy, and even seizures due to water moving out of cells. Conversely, hypoosmolarity results in cellular swelling, which can lead to cellular dysfunction and potentially life-threatening conditions like cerebral edema. Both conditions disrupt fluid balance and can significantly impair physiological functions.

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