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Demyelination and denervation bring about muscle weakness, loss of sensation, or paralysis because the affected nerves cannot transmit signals to muscles.

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What is the neuronal basis of denervation hypersensitivity?

Denervation hypersensitivity occurs in multiple sclerosis. In multiple sclerosis demyelination of oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system result in disruption of communication between upper motor neurons in the brain and the lower motor neurons in the gray matter of the spinal cord. The end result is denervation hypersensitivity with physical symptoms of increased muscle tone, difficulty controlling muscles, exaggerated reflexes, and muscle spasms.


What causes many small foci of demyelination all over the brain in both hemisphere besided ms?

Small foci of demyelination in both hemispheres of the brain can be caused by conditions such as acute disseminated encephalomyelitis (ADEM), neuromyelitis optica (NMO), leukodystrophies, and infections like progressive multifocal leukoencephalopathy (PML). These conditions can present with similar patterns of demyelination to multiple sclerosis (MS) but have distinct underlying causes and clinical features. A detailed evaluation by a neurologist and additional tests such as MRI, lumbar puncture, and blood tests are typically needed to differentiate between these conditions.


Autoimmune disorder with extensive demyelination?

Multiple sclerosis is an autoimmune disorder characterized by extensive demyelination of the nerve fibers in the central nervous system. The immune system mistakenly attacks the myelin sheath, leading to impaired nerve function and potential neurological symptoms such as weakness, numbness, and vision problems. Treatment often involves medications to reduce inflammation and modify the immune response.


Few small ill defined irregular t2 flair hyperintensities subcortical white matter of bilateral frontal lobes ischemic demyelination is likely?

What treatment to be given in this case


What happens if oligodendrocytes of the CNS are damaged?

demyelinating disease: multiple sclerosis, catastrophe, and cerebral palsy.

Related Questions

What is active denervation?

denervation means "nerve injury"


What is the neuronal basis of denervation hypersensitivity?

Denervation hypersensitivity occurs in multiple sclerosis. In multiple sclerosis demyelination of oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system result in disruption of communication between upper motor neurons in the brain and the lower motor neurons in the gray matter of the spinal cord. The end result is denervation hypersensitivity with physical symptoms of increased muscle tone, difficulty controlling muscles, exaggerated reflexes, and muscle spasms.


What has the author Carl Damien Enna written?

Carl Damien Enna has written: 'Peripheral denervation of the foot' -- subject(s): Foot, Innervation, Denervation, Surgery, Foot Deformities, Complications, Adverse effects, Rehabilitation


What does demyelination affect?

The myelin sheath that surrounds the nerve


Which condition is characterized by scattered patches of demyelination of nerve fibers of the brain?

Multiple sclerosis is a condition characterized by scattered patches of demyelination of nerve fibers in the brain and spinal cord. This demyelination disrupts the ability of nerve fibers to conduct electrical impulses, leading to various neurological symptoms.


What condition causes patchy demyelination in the brain and spinal cord?

Multiple Sclerosis.


What is Vasculitic process with resultant focal demyelination?

A vasculitic process is something that was going on in your body that caused inflammation of vessels. Focal demyelination is a small area of loss of the "insulating" fatty layer that covers the nerves.


What has the author Keith Whelpdale written?

Keith Whelpdale has written: 'The effect of primary afferent denervation on wound healing'


Is loss of its nerve supply would cause denervation atrophy and paralysis of the skeletal muscle involved true?

Yes it is true.


Which of the following statements does not describe denervation hypersensitivity?

Autonomic target tissues become more sensitive than normal to stimulating agents.


Condition characterized by scattered patches of demyelination of nerve fibers of the brain and spinal cord?

multiple sclerosis


Which condition is characterized by scattered patches of demyelination of the nerve fibers of the brain and spinal cord?

multiple sclerosis