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What is the neuronal basis of denervation hypersensitivity?
Denervation hypersensitivity occurs in multiple sclerosis. In multiple sclerosis demyelination of oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system result in disruption of communication between upper motor neurons in the brain and the lower motor neurons in the gray matter of the spinal cord. The end result is denervation hypersensitivity with physical symptoms of increased muscle tone, difficulty controlling muscles, exaggerated reflexes, and muscle spasms.
What is Without evidence of active denervation?
Without evidence of active denervation refers to a clinical or diagnostic finding indicating that there are no signs of ongoing nerve damage or dysfunction in a patient. This means that nerve signals are likely intact and functioning normally, as there is no indication of muscle atrophy or weakness due to nerve injury. This phrase is often used in electromyography (EMG) reports or neurological assessments to clarify the status of nerve health. In the absence of active denervation, other conditions may need to be considered for any symptoms a patient is experiencing.
What is demyelination of tissue around the axons of CNS neuronscalled?
Demyelination of tissue around the axons of CNS neurons is called multiple sclerosis (MS). In MS, the immune system mistakenly attacks the myelin sheath, leading to disrupted communication between the brain and other parts of the body. This condition can result in a variety of neurological symptoms, including fatigue, motor impairment, and sensory disturbances. Demyelination can also occur in other conditions, but MS is the most well-known.
What causes many small foci of demyelination all over the brain in both hemisphere besided ms?
Small foci of demyelination in both hemispheres of the brain can be caused by conditions such as acute disseminated encephalomyelitis (ADEM), neuromyelitis optica (NMO), leukodystrophies, and infections like progressive multifocal leukoencephalopathy (PML). These conditions can present with similar patterns of demyelination to multiple sclerosis (MS) but have distinct underlying causes and clinical features. A detailed evaluation by a neurologist and additional tests such as MRI, lumbar puncture, and blood tests are typically needed to differentiate between these conditions.
Autoimmune disorder with extensive demyelination?
Multiple sclerosis is an autoimmune disorder characterized by extensive demyelination of the nerve fibers in the central nervous system. The immune system mistakenly attacks the myelin sheath, leading to impaired nerve function and potential neurological symptoms such as weakness, numbness, and vision problems. Treatment often involves medications to reduce inflammation and modify the immune response.
What is active denervation?
denervation means "nerve injury"
What is the neuronal basis of denervation hypersensitivity?
Denervation hypersensitivity occurs in multiple sclerosis. In multiple sclerosis demyelination of oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system result in disruption of communication between upper motor neurons in the brain and the lower motor neurons in the gray matter of the spinal cord. The end result is denervation hypersensitivity with physical symptoms of increased muscle tone, difficulty controlling muscles, exaggerated reflexes, and muscle spasms.
What has the author Carl Damien Enna written?
Carl Damien Enna has written: 'Peripheral denervation of the foot' -- subject(s): Foot, Innervation, Denervation, Surgery, Foot Deformities, Complications, Adverse effects, Rehabilitation
What does demyelination affect?
The myelin sheath that surrounds the nerve
Which condition is characterized by scattered patches of demyelination of nerve fibers of the brain?
Multiple sclerosis is a condition characterized by scattered patches of demyelination of nerve fibers in the brain and spinal cord. This demyelination disrupts the ability of nerve fibers to conduct electrical impulses, leading to various neurological symptoms.
What does demyelination mean?
Demyelination refers to the loss or damage of the myelin sheath, a protective covering that surrounds nerve fibers in the central and peripheral nervous systems. This process disrupts the efficient transmission of electrical signals between neurons, leading to neurological symptoms and impairments. Conditions such as multiple sclerosis are characterized by demyelination, which can result in various physical and cognitive challenges.
What is Vasculitic process with resultant focal demyelination?
A vasculitic process is something that was going on in your body that caused inflammation of vessels. Focal demyelination is a small area of loss of the "insulating" fatty layer that covers the nerves.
What has the author Keith Whelpdale written?
Keith Whelpdale has written: 'The effect of primary afferent denervation on wound healing'
What condition causes patchy demyelination in the brain and spinal cord?
Multiple Sclerosis.
Is loss of its nerve supply would cause denervation atrophy and paralysis of the skeletal muscle involved true?
Yes it is true.
What is Without evidence of active denervation?
Without evidence of active denervation refers to a clinical or diagnostic finding indicating that there are no signs of ongoing nerve damage or dysfunction in a patient. This means that nerve signals are likely intact and functioning normally, as there is no indication of muscle atrophy or weakness due to nerve injury. This phrase is often used in electromyography (EMG) reports or neurological assessments to clarify the status of nerve health. In the absence of active denervation, other conditions may need to be considered for any symptoms a patient is experiencing.
Which of the following statements does not describe denervation hypersensitivity?
Autonomic target tissues become more sensitive than normal to stimulating agents.
