Demyelination and denervation bring about muscle weakness, loss of sensation, or paralysis because the affected nerves cannot transmit signals to muscles.
Denervation hypersensitivity occurs in multiple sclerosis. In multiple sclerosis demyelination of oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system result in disruption of communication between upper motor neurons in the brain and the lower motor neurons in the gray matter of the spinal cord. The end result is denervation hypersensitivity with physical symptoms of increased muscle tone, difficulty controlling muscles, exaggerated reflexes, and muscle spasms.
Small foci of demyelination in both hemispheres of the brain can be caused by conditions such as acute disseminated encephalomyelitis (ADEM), neuromyelitis optica (NMO), leukodystrophies, and infections like progressive multifocal leukoencephalopathy (PML). These conditions can present with similar patterns of demyelination to multiple sclerosis (MS) but have distinct underlying causes and clinical features. A detailed evaluation by a neurologist and additional tests such as MRI, lumbar puncture, and blood tests are typically needed to differentiate between these conditions.
Multiple sclerosis is an autoimmune disorder characterized by extensive demyelination of the nerve fibers in the central nervous system. The immune system mistakenly attacks the myelin sheath, leading to impaired nerve function and potential neurological symptoms such as weakness, numbness, and vision problems. Treatment often involves medications to reduce inflammation and modify the immune response.
What treatment to be given in this case
demyelinating disease: multiple sclerosis, catastrophe, and cerebral palsy.
denervation means "nerve injury"
Denervation hypersensitivity occurs in multiple sclerosis. In multiple sclerosis demyelination of oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system result in disruption of communication between upper motor neurons in the brain and the lower motor neurons in the gray matter of the spinal cord. The end result is denervation hypersensitivity with physical symptoms of increased muscle tone, difficulty controlling muscles, exaggerated reflexes, and muscle spasms.
Carl Damien Enna has written: 'Peripheral denervation of the foot' -- subject(s): Foot, Innervation, Denervation, Surgery, Foot Deformities, Complications, Adverse effects, Rehabilitation
The myelin sheath that surrounds the nerve
Multiple sclerosis is a condition characterized by scattered patches of demyelination of nerve fibers in the brain and spinal cord. This demyelination disrupts the ability of nerve fibers to conduct electrical impulses, leading to various neurological symptoms.
Multiple Sclerosis.
A vasculitic process is something that was going on in your body that caused inflammation of vessels. Focal demyelination is a small area of loss of the "insulating" fatty layer that covers the nerves.
Keith Whelpdale has written: 'The effect of primary afferent denervation on wound healing'
Yes it is true.
Autonomic target tissues become more sensitive than normal to stimulating agents.
multiple sclerosis
multiple sclerosis