What is Discohesive clusters of atypical epithelial cells seen?

Answer 1

The short answer is, a problem for whatever the sample was removed from. Breaking down the phrase, we have:

1. Discohesive (pronounced dis-co-HE-sive) - the cells are not organized (cohesive); the cells are arranged in an abnormal pattern

2. Clusters - the cells are making little islands of themselves rather than arranging as a continuous sheet or structure

3. Atypical - not normal; showing signs of genetic or structural changes

4. Epithelial - a cell classification associated with the linings of organs as well as with the production of enzymes or hormones

Putting everything back together, you have abnormal, organ lining or organ forming cells that are not organized and are gathered into little groups. In practical terms, this is likely either a cancer or a pre-cancerous growth that is invading and expanding into the local normal tissues.

Answer 2

Discohesive clusters of atypical epithelial cells suggest a lack of adherence between the cells, which is abnormal. This finding can be concerning for malignancy or a precancerous condition and may warrant further evaluation, such as a biopsy, to determine the cause. Additional testing and management would be based on the underlying diagnosis.