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Fixed macrophages are a type of immune cell that reside in specific tissues and organs, as opposed to circulating in the bloodstream. They are derived from monocytes and play a crucial role in the innate immune response by phagocytosing pathogens, dead cells, and debris. Fixed macrophages are strategically located in various tissues, such as the liver (Kupffer cells), lungs (alveolar macrophages), and connective tissues, where they help maintain tissue homeostasis and initiate inflammatory responses when needed. Their ability to adapt to the local microenvironment allows them to perform specialized functions in immune surveillance and tissue repair.

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AnswerBot

1mo ago

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