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Something tells me that trisomy 21 is not really the most common, but it is the common among babies that actually live. Other trisomies common among live births are those of the 13th and 18th chromosome. Trisomy 16 is the most common known disorder of miscarried fetuses. Trisomy is caused by nondisjunction of a pair of chromosomes during meiosis or mitosis. What causes nondisjunction? If we could figure that out, we might be able put trisomies in the past.

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16y ago

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What are the history of disease?

It is named after John H. Edwards, who first described the syndrome in 1960. It is the second most common autosomal trisomy, after Down Syndrome, that carries to term.


The most common autosomal abnormality is seen is a person with?

The most common autosomal abnormality seen in a person is Trisomy 21, which causes Down syndrome. This occurs due to an extra copy of chromosome 21, leading to developmental delays and physical characteristics like slanted eyes and a flat facial profile.


What word is used to describe someone who has three instead of a pair of autosomes?

That person is known as having an autosomal trisomy.


What is the different autochromosomal abnormalities?

Common autosomal chromosomal abnormalities include Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), Patau syndrome (trisomy 13), and Turner syndrome (monosomy X). These abnormalities result from errors in chromosome number, leading to characteristic physical and developmental features. Diagnosis is often made through genetic testing such as karyotyping or chromosomal microarray analysis.


What kind of diseases are the most common genetic diseases (?

Recessive Autosomal


What is the most common form of aneuploidy?

autosomal


What kind of diseases of the most common genetic diseases?

recessive autosomal


What is the inheritance pattern for sickle cell disease?

Down syndrome is due to trisomy condition of chromosome 21. That is 2n+ 1 condition. leads to mental retardation, reduced IQ pwer etc


Is Edwards syndrome autosomal or sex-linked?

Down Syndrome is a trisomy of the 21st chromosome as opposed to an allelic inheritance through the X chromosome. Trisomy is a somatic disorder caused by improper division during gametogenesis (usually of the ovum) that results in 3 copies of the 21st chromosome in the egg once it is fertilized.


What is the least-common trisomy?

Trisomy 13 Trisomy 13, or Patau�s syndrome is the least common of the live-born trisomy disorders, with an incidence of 1 in 5000 to 1 in 2,000 live births, with affected males equal to affected females. 75% of trisomy 13 cases are due to maternal NDJ, 20% are due to a translocation, and 5% are due to mosaicism. The major midline dysmorphic features of trisomy 13 are due to a defect in the fusion of the midline prechordial mesoderm in the first three weeks of gestation. Trisomy 13 tends to present with more severe craniofacial and midline defects than are found in Trisomy 18 or 21. Trisomy 13 has the following clinical features: # Holoporsencephaly # Polydactly # Seizures # Deafness # Microcephaly # Midline Cleft lip # Midline Cleft palate # Abnormal ears # Sloping forehead # Omphalocele # Cardiac and renal anomalies # Mental retardation. Trisomy 13 is also confirmed by karyotype with FISH analysis. 44% of these patients die within 1 month, and > 70% die within one year. Severe mental retardation exists in all survivors as per (http://pedclerk.bsd.uchicago.edu/chromosomalabnormalities.html)


Is color blindness monosomy or trisomy?

trisomy


Can trisomy 18 be cured?

There is no cure for trisomy 18