What is a gene clustering?

Answer 1

Simplistically it's grouping of genes from your biological organism of interest.

This grouping can be carried out depending on your pre-requisites i.e your aim or scope of research. Various software's have various tabs and tools to carry the clustering where in you have to specify the parameters.

Normally clustering is carried out to differentiate gene expression patterns from your experimental sample to your control sample.

Depending on the software you use and the parameters you set, you get different kinds of gene clusters with similar patterns or opposite patterns.

e.g:- You can clusters of genes with an increased expression level (this increase parameter can be set by you, say, 2 fold, 3 fold, 100 fold etc.) in your experimental sample to that of your control. Also you can cluster genes based on their biological function and then study their expression patterns.

Hope this provides a brief picture. Any further queries can be sent to dathaa99atgmaildotcom.

Answer 2

Gene clustering refers to a phenomenon where genes that are physically close to each other on a chromosome are more likely to be co-expressed or co-regulated. This can indicate that these genes are functionally related or participate in the same biological process. Gene clustering is often observed in prokaryotic genomes but can also occur in eukaryotic organisms.