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A microsphere is a small spherical particle typically ranging from 1 to 1000 micrometers in size, composed of polymer or other materials that can encapsulate drugs or other substances. Coacervates are liquid droplets formed by the phase separation of two immiscible liquids, typically polymers, resulting in a dense liquid phase surrounded by a dilute phase. Coacervates have been studied for their ability to encapsulate biomolecules and act as a delivery system in biotechnology and pharmaceutical applications.

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What are Tiny droplet formed by chains of amino acids that gather together in water?

Peptide nanotubes are tiny droplets formed by chains of amino acids that self-assemble and gather together in water. These structures have unique properties and potential applications in various fields, including medicine and materials science.


What is the relationship between micro-sphere and coacervate?

Micro-spheres are small spherical particles, while coacervates are dense liquid phase droplets formed by phase separation in a colloid system. Micro-spheres can encapsulate coacervates, providing a protective environment for the coacervate to remain stable and function effectively. The use of micro-spheres to encapsulate coacervates is a common strategy in drug delivery and other applications requiring controlled release.


How was coacervates formed?

Coacervates are formed through the phase separation of a solution containing hydrophilic and hydrophobic molecules. When the hydrophobic molecules aggregate together, they form a coacervate phase separate from the rest of the solution. This aggregation can be driven by various factors like changes in temperature, pH, or salt concentration.


How would you classify gum Arabic and gelatin in terms of organic molecules?

Gum Arabic is a complex polysaccharide composed of various sugar units, making it an organic compound. Gelatin is a protein derived from collagen, which is also an organic molecule. Both gum Arabic and gelatin are considered organic molecules due to their carbon-based structures.


How does pH affect hydrogel?

pH has a vital role in formation of coacervates. pH changes the surface charge of the polymer in its solution. When two types of charges are present in the solution, the environment prefers binding and crosslinking. When this sort of aggregation develops, we see droplets of coacervates in the system. now How pH changes the surface charge density? The total charge of the polymer solution(system) is zero at its pI or isoelectric point which is fixed for a particular polyampholytic polymer like gelatin. However no pI exists for purely anionic and purely cationic polymers. For example, Agar is a polyanionic polymer. When the pH of solution is less than the PI, the positive charges get dominated over it and vice versa. These charges affect the binding property in the system and hence the coacervate formation. Answered by Shilpi Boral.

Related Questions

What is the difference between microsphere and coacervate?

A coacervate is a tiny spherical droplet of assorted organic molecules (specifically, lipid molecules) which is held together by hydrophobic forces from a surrounding liquid. Coacervates measure 1 to 100 micrometers across, possess osmotic properties and form spontaneously from certain dilute organic solutions. Have no membrane. Microspheres have a double membrane.


Which topic shoul you choose for your project work in Pharmaceutics branch for MPharm?

microsphere


What is a tiny droplet formed by chains of amino acids that gather together in water?

microsphere


Tiny bubbles formed by large organic molecules?

Proteinoid microspheres (or just a microsphere if you were going for a general answer)


What does coacervate mean?

A coacervate is a cluster or droplet formed by the aggregation of molecules, often seen in a colloidal system. These clusters are held together by weak interactions like van der Waals forces or hydrophobic interactions. Coacervates are often used in biotechnology and pharmaceuticals for encapsulating molecules or creating controlled release systems.


Why is gum Arabic used in complex coacervation?

Gum Arabic is used in complex coacervation because of its ability to form a stable colloidal dispersion. When combined with a cationic polymer, such as gelatin, it can create a dense and stable coacervate phase due to attractive electrostatic interactions. This coacervate can be used for encapsulation purposes in the food and pharmaceutical industries.


What are Tiny droplet formed by chains of amino acids that gather together in water?

Peptide nanotubes are tiny droplets formed by chains of amino acids that self-assemble and gather together in water. These structures have unique properties and potential applications in various fields, including medicine and materials science.


What is microsphere?

it is charactirestically free flowing powers cosisiting of synthetic polimer which are biodedegradable in nature and ideally having a particle size less than 200 micro mtr.


What is a microsphere?

small spererical particles which can be manufactured from natural and synthetic materials. It's diametres are in the micrometre range(typically 1 μm to 1000 μm (1 mm).


What has the author I Spradley written?

I. Spradley has written: 'Integrated Cryogenic Experiment (ICE) microsphere investigation' -- subject(s): Insulation, Microgravity, Microparticles, Weightlessness, Liquid helium, Cryogenic equipment, Cryogenic storage


What is the relationship between micro-sphere and coacervate?

Micro-spheres are small spherical particles, while coacervates are dense liquid phase droplets formed by phase separation in a colloid system. Micro-spheres can encapsulate coacervates, providing a protective environment for the coacervate to remain stable and function effectively. The use of micro-spheres to encapsulate coacervates is a common strategy in drug delivery and other applications requiring controlled release.


How was coacervates formed?

Coacervates are formed through the phase separation of a solution containing hydrophilic and hydrophobic molecules. When the hydrophobic molecules aggregate together, they form a coacervate phase separate from the rest of the solution. This aggregation can be driven by various factors like changes in temperature, pH, or salt concentration.