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There are many reasons why buffers are important in the body.

Buffers are chemicals that reduce major pH changes in your body fluids (blood, intracellular fluid, interstitial fluid). An example of pH change is during strenuous exercise when your skeletal cells produce lots of carbon dioxide which enters the blood and forms carbonic acid. This gives off hydrogen ions and acidifies the blood.

It's very important to minimise this acidification as there are many components inside your body and inside cells that are pH sensitive. Enzymes have optimum pH levels at which they work best in and if the pH deviates too much then the enzymes won't work as well and your body can't function properly.

Other proteins are pH sensitive as excess hydrogen or hydroxyl ions begin to interfere with intra-molecular interactions such as ionic and hydrogen bonding. When these become disrupted then the protein can denature (lose its structure) and thus loses its function.

Therefore it's very important to keep the pH of our body fluids within a very narrow range so all our cell components work optimally.

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14y ago

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