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A calcified granuloma in segment V of the liver is a localized area of inflammation that has undergone calcification, often as a result of a previous infection or inflammatory process. These granulomas can arise from conditions like tuberculosis, sarcoidosis, or prior infections that lead to the deposition of calcium salts in the affected tissue. They are typically asymptomatic and may be discovered incidentally on imaging studies. While generally benign, the presence of a granuloma should be evaluated to rule out any underlying pathology.

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