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Cyclic AMP, or cAMP, is a small molecule that plays a critical role in cellular signaling. It is synthesized from ATP by the enzyme adenylate cyclase and acts as a second messenger to regulate various cellular processes, including metabolism, gene expression, and cell growth. The concentration of cAMP in a cell can vary depending on external signals and internal regulatory mechanisms.
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Explain how cyclic AMP and catabolite activator protein are affected by glucose concentration?
Cyclic AMP accumulates when the glucose concentration is scarce. If the glucose concentration increases, the cAMP concentration falls, and without it, CAP (catabolite activator portein) detaches from the operon and becomes inactive.
What is Cyclic Amp cyclic GMP and PIP2 calcium?
Cyclic AMP is a form of adenylic acid responsible for regulating enzyme-catalyzed processes in living cells while PIP2 calcium is a membrane phospholipid.
Does cyclic amp bind to calmodulin?
No, calcium bonds to calmodulin
How would a molecule that mimics cyclic AMP affect an olfactory receptor?
A molecule that mimics cyclic AMP can activate olfactory receptors by binding to their target site, triggering a cascade of intracellular signals similar to the natural activation of the receptor by cyclic AMP. This can lead to the perception of a smell even in the absence of the actual odorant molecule.
Who discovered cyclic AMP?
Cyclic AMP (cAMP) was discovered by Earl Wilbur Sutherland Jr., an American pharmacologist, in 1957. He received a Nobel Prize in 1971 for his discoveries related to the mechanisms of action of hormones.
Did sutherland discover that epinephrine elevates the cytosolic concentration of cyclic AMP?
yes
Explain how cyclic AMP and catabolite activator protein are affected by glucose concentration?
Cyclic AMP accumulates when the glucose concentration is scarce. If the glucose concentration increases, the cAMP concentration falls, and without it, CAP (catabolite activator portein) detaches from the operon and becomes inactive.
Why is cyclic AMP a secondary messenger?
because original message is carried by hormone, which cant act directly, so in turn it activates cyclic AMP.
What is Cyclic Amp cyclic GMP and PIP2 calcium?
Cyclic AMP is a form of adenylic acid responsible for regulating enzyme-catalyzed processes in living cells while PIP2 calcium is a membrane phospholipid.
Does cyclic amp bind to calmodulin?
No, calcium bonds to calmodulin
How would a molecule that mimics cyclic AMP affect an olfactory receptor?
A molecule that mimics cyclic AMP can activate olfactory receptors by binding to their target site, triggering a cascade of intracellular signals similar to the natural activation of the receptor by cyclic AMP. This can lead to the perception of a smell even in the absence of the actual odorant molecule.
What does C in the test CRP stands for?
Cyclic AMP Receptor Protein
Who discovered cyclic AMP?
Cyclic AMP (cAMP) was discovered by Earl Wilbur Sutherland Jr., an American pharmacologist, in 1957. He received a Nobel Prize in 1971 for his discoveries related to the mechanisms of action of hormones.
What has the author G Alan Robison written?
G. Alan Robison has written: 'Cyclic AMP' -- subject(s): Cyclic adenylic acid
What is the the role of cyclic AMP in cell proliferation?
Cyclic AMP is a secondary messenger that regulates cell proliferation by activating protein kinase A (PKA). PKA then phosphorylates target proteins involved in cell cycle progression, gene expression, and other cellular processes that drive cell proliferation. Overall, cyclic AMP signaling pathways play a crucial role in coordinating the cell's response to proliferative signals.
What hormone lowers c AMP concentration in liver cells is?
The hormone that lowers cyclic AMP (cAMP) concentration in liver cells is insulin. Insulin activates phosphodiesterase, an enzyme that breaks down cAMP, leading to a decrease in its levels. This action counteracts the effects of glucagon and catecholamines, which typically raise cAMP levels and promote glucose release from the liver. As a result, insulin plays a crucial role in regulating glucose homeostasis.
What is cyclic AMP produced by?
Cyclic AMP (cAMP) is produced by the enzyme adenylate cyclase, which converts ATP into cAMP in response to various signaling molecules such as hormones or neurotransmitters. The cAMP molecule then acts as a second messenger to relay extracellular signals into the cell to regulate various cellular processes.
