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Indolent systemic mastocytosis (ISM) is a type of mastocytosis characterized by the accumulation of mast cells in various tissues, including the skin, bone marrow, and internal organs, without significant organ dysfunction. Patients may experience symptoms such as skin rashes, flushing, gastrointestinal issues, and anaphylactic reactions, but these symptoms are generally mild and manageable. Unlike aggressive forms of mastocytosis, ISM typically has a better prognosis and patients often lead normal lives with appropriate treatment and management. Diagnosis is confirmed through a combination of clinical evaluation, skin biopsies, and blood tests to detect elevated levels of mast cell mediators.

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1w ago

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What is the typical prognosis for systemic mastocytosis?

The prognosis for systemic mastocytosis varies depending on the subtype and individual characteristics of the disease. Patients with aggressive forms of systemic mastocytosis may have a poorer prognosis compared to those with indolent forms. Regular monitoring and appropriate management by a healthcare team familiar with the condition can help improve outcomes.


Is systemic mastocytosis blood cancer?

No. There is a rare form of leukemia which is caused by systemic mastocytosis but most of us with the disease will not get it.


What do patients with systemic mastocytosis often develop?

Many patients with systemic mastocytosis also develop urticaria pigmentosa.


What pain does mastocytosis cause?

People with systemic mastocytosis have bone and joint pain.


What are the chances that systemic mastocytosis will develop from mastocytoma?

Mastocytoma and urticaria pigmentosa rarely if ever, develop into systemic mastocytosis, and both spontaneously improve over time.


I have mastocytosis and i was send for a bone marrow?

systemic mastocytosis is diagnosed via bone marrow biopsy. If mast cells are found in the bone marrow and you have another symptom that fits the criteria then you will be diagnosed with systemic mastocytosis. You can read more about it at www.tmsforacure.org.


Are there other rashes that mimic mastocytosis rashes?

Yes, I am sure thre are some which last as long as a chronic systemic mastocytosis


What is the cause of mastocytosis?

The cause of mastocytosis is unknown.


Mastocytosis comes in how many forms?

Mastocytosis comes in three forms.


Is anyone familiar with mastocytosis?

Yes I am familiar with mastocytosis. Val walusia@yahoo.com


How do use indolent in a sentence?

you are very indolent


What does indolent mean?

Indolence is habitual sloth or laziness. An indolent person is an unmotivated person.