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The cells in the skin epithelium are cuboid, mostly dead, with very low vascularity and saturated with keratin which prevents not only gases from diffusing in and out of the body, but also prevents liquids and solutes from moving out of the body.

There are, anyway, epithelia that allow oxygen flow, like the lung's epithelium, since epithelium is a kind of tissue that covers others, therefore, not only skin is epithelium.

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