Its molecular shape is altered so the substrate cannot fit to its active site
Enzymes are proteins that help speed up the the rate of chemical reactions in the human body. Enzymes possess a specific shape and this shape fits into the substrate. When an enzyme becomes denatured, it loses its shape and thus it cannot function effectively. Enzymes may become denatured due to high temperatures or changes in the pH.
the active site would no longer fit into the substrate
When an enzyme loses its native conformation, it results in a loss of its specific three-dimensional shape essential for its biological activity. This process, known as denaturation, can be caused by factors such as temperature, pH changes, or exposure to certain chemicals. Denaturation typically leads to a loss of enzyme function due to the disruption of the active site necessary for substrate binding and catalysis.
Shape. When an enzyme is overheated the bonds between molecules that make up the enzyme breaks, this changes the shape of the enzyme's active site. And as the enzyme is highly specific and would only work on one substrate which fits its active site, the enzyme will be totally denatured and won't activate anymore if it loses its shape.
Its molecular shape is altered so the substrate cannot fit to its active site
denatured
At a high ion concentration, the ion interfere with the bonds between the side groups of the amino acids making up the enzyme (which is a protein). This causes the enzyme to lose its shape, called denaturation. If the enzyme loses its shape, it can no longer accept and react substrate, so the rate of enzyme activity decreases.
Enzymes are proteins that help speed up the the rate of chemical reactions in the human body. Enzymes possess a specific shape and this shape fits into the substrate. When an enzyme becomes denatured, it loses its shape and thus it cannot function effectively. Enzymes may become denatured due to high temperatures or changes in the pH.
the active site would no longer fit into the substrate
When an enzyme loses its native conformation, it results in a loss of its specific three-dimensional shape essential for its biological activity. This process, known as denaturation, can be caused by factors such as temperature, pH changes, or exposure to certain chemicals. Denaturation typically leads to a loss of enzyme function due to the disruption of the active site necessary for substrate binding and catalysis.
When an enzyme is denatured the active site which allows it to catalyze reactions is destroyed, rendering the enzyme useless. This process is irreversible but the remains are recycled to form new enzymes.
Shape. When an enzyme is overheated the bonds between molecules that make up the enzyme breaks, this changes the shape of the enzyme's active site. And as the enzyme is highly specific and would only work on one substrate which fits its active site, the enzyme will be totally denatured and won't activate anymore if it loses its shape.
The enzymatic function of the enzyme is lost when it is denatured. Of course this also means that the enzyme's structure has changed too. Depending on the severity of the denaturation, the enzyme may be able to revert back to its original structure once the abused conditions are removed.
Enzymes are made up of proteins. At a high temperature, the polypeptide chains of the enzyme are unfolded hence it loses its specific 3D configuration and active site, and is denatured.
When this happens to a protein, it is said to denature.Denature is caused commonly by very high or low temperature,concentrated acids or bases.Denature by high temperature is irrevesible.
When an enzyme goes too far from its ideal temperature or pH, it can become denatured, meaning it loses its shape and ability to function properly. This can result in the enzyme being unable to catalyze reactions effectively or at all.