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Mutant isolation refers to the process of selecting out individual organisms (plant, animal, or microbial) depending upon genetic mutations. For example, staphylococcus aureus, a bacterium, is normally susceptible to a penicillin-derivative called methicillin. If you take a culture of s. aureus growing in a liquid medium, and slowly started adding increasing doses of methicillin, you will gradually kill off the normal s. aureus and leave behind those which have mutated in such a way as to be resistant to the antibiotic.

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15y ago

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