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Negative feedback is a system by which internal conditions are kept within set limits. For example your home thermostat has a thermometer which detects when the temperature of your home drops below room temperature which triggers a response, the heating is turned on. When your home is brought back to room temperature, the response is turned off to prevent the temperature getting too high.

In living organisms examples include: solute concentration of the blood/tissue fluid (which affects the water potential of cells and the cytoplasmic reactions that can occur), internal body temperature (must be kept close to the optimal operating temperature of metabolic enzymes within the cells), changes in pH etc.

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13y ago

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