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WAF1is also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1. It is a protein that in humans is encoded by the cdkn1Agene located on chromosome 6. p-21, the product of waf gene is the inhibitor of cdk4/cyclin-D-1 complex. It inactivates cdk4/cyclin-D-1 complex and the cell cycle is arrested at G1 phase.

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13y ago

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