One molecule of pyruvate, which is the end product of glycolysis, can yield a total of approximately 12.5 ATP molecules when fully oxidized in the presence of oxygen through the processes of the citric acid cycle and oxidative phosphorylation. Specifically, each pyruvate is converted into acetyl-CoA, which enters the citric acid cycle, producing NADH and FADH₂ that are then used in the electron transport chain to generate ATP. Additionally, the complete oxidation of one pyruvate molecule also results in the production of carbon dioxide and water.
Every glucose molecule that enters glycolysis yields two molecules of pyruvate, two molecules of ATP (net gain), and two molecules of NADH. Glycolysis occurs in the cytoplasm and is the first step in both aerobic and anaerobic respiration. Additionally, it involves a series of enzymatic reactions that convert glucose into pyruvate while extracting energy.
During the bridge reactions, also known as the pyruvate decarboxylation process, no ATP is directly produced. Instead, this process converts pyruvate into acetyl-CoA while generating one molecule of NADH for each pyruvate molecule, which can later be used to produce ATP in the electron transport chain. Since each glucose molecule yields two pyruvate molecules, this results in two NADH molecules per glucose, contributing to ATP production indirectly.
Pyruvate processing, which occurs in the mitochondria, converts pyruvate into acetyl-CoA. During this process, one molecule of carbon dioxide is released for each pyruvate, and one NADH is generated. The acetyl-CoA then enters the citric acid cycle, where it plays a crucial role in cellular respiration. Overall, pyruvate processing prepares the carbon skeleton for further energy extraction.
The Krebs cycle, also known as the citric acid cycle, must run once for each molecule of pyruvate. Since one glucose molecule produces two pyruvate molecules during glycolysis, the Krebs cycle runs twice for each glucose molecule. Therefore, for one molecule of pyruvate, the cycle runs just once.
Pyruvate dehydrogenase complex react with pyruvate to form acetyl-CoA
Every glucose molecule that enters glycolysis yields two molecules of pyruvate, two molecules of ATP (net gain), and two molecules of NADH. Glycolysis occurs in the cytoplasm and is the first step in both aerobic and anaerobic respiration. Additionally, it involves a series of enzymatic reactions that convert glucose into pyruvate while extracting energy.
During the bridge reactions, also known as the pyruvate decarboxylation process, no ATP is directly produced. Instead, this process converts pyruvate into acetyl-CoA while generating one molecule of NADH for each pyruvate molecule, which can later be used to produce ATP in the electron transport chain. Since each glucose molecule yields two pyruvate molecules, this results in two NADH molecules per glucose, contributing to ATP production indirectly.
Pyruvate processing, which occurs in the mitochondria, converts pyruvate into acetyl-CoA. During this process, one molecule of carbon dioxide is released for each pyruvate, and one NADH is generated. The acetyl-CoA then enters the citric acid cycle, where it plays a crucial role in cellular respiration. Overall, pyruvate processing prepares the carbon skeleton for further energy extraction.
Acetyl coenzyme A is produced twice from one molecule of glucose in the process of glycolysis and the citric acid cycle. Each glucose molecule is broken down into two molecules of pyruvate during glycolysis, and each pyruvate molecule is converted to one molecule of acetyl CoA before entering the citric acid cycle.
The Krebs cycle, also known as the citric acid cycle, must run once for each molecule of pyruvate. Since one glucose molecule produces two pyruvate molecules during glycolysis, the Krebs cycle runs twice for each glucose molecule. Therefore, for one molecule of pyruvate, the cycle runs just once.
Pyruvate dehydrogenase complex react with pyruvate to form acetyl-CoA
The metabolic end product of aerobic glycolysis is pyruvate. From one molecule of glucose, two molecules of pyruvate are produced through the process of glycolysis.
Pyruvate is an end product of glycolysis.
The enzyme that converts pyruvate into acetyl-CoA is pyruvate dehydrogenase. This multienzyme complex is responsible for catalyzing the conversion of pyruvate into acetyl-CoA, which is a key step in the metabolism of carbohydrates to produce energy.
The products of acetyl CoA formation from a molecule of pyruvate are acetyl CoA, NADH, and carbon dioxide. This process occurs during the mitochondrial pyruvate dehydrogenase complex reaction, where pyruvate is converted to acetyl CoA by a series of enzymatic reactions.
Enzymes that are involved in the breakdown of pyruvate include pyruvate dehydrogenase complex (PDC) and pyruvate carboxylase. These enzymes are crucial in converting pyruvate into acetyl-CoA to enter the citric acid cycle for further energy production.
Acetyl-CoA is the metabolite that enters the citric acid cycle and is formed in part by the removal of a carbon from one molecule of pyruvate through a process called pyruvate decarboxylation.