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The MAC nucleus, or the medial accessory nucleus, is a part of the brain located in the medullary region of the brainstem. It plays a crucial role in the integration of sensory and motor functions, particularly in relation to the regulation of autonomic responses and reflexes. This nucleus is involved in processing information from the cranial nerves and contributes to various physiological processes, including cardiovascular and respiratory regulation. Its exact functions and connections continue to be an area of research in neuroscience.

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