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The biggest disadvantage of using iPSCs (induced pluripotent stem cells) for medical treatments is the risk of tumor formation. Since iPSCs can proliferate indefinitely and differentiate into various cell types, there is a potential for uncontrolled growth, leading to teratomas or other malignancies. Additionally, the processes involved in reprogramming somatic cells into iPSCs can introduce genetic and epigenetic abnormalities, which may compromise safety and efficacy in therapeutic applications.

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1w ago

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