I searched for this mechanism for along time & I finally found it at this site:
http://www.bioportfolio.com/search/reaction_mechanism_for_salicylic_acid_acetic_anhydride.html
at this site under the category of:
synthesis of aspirin
the file that will be downloaded contains the mechanism
hope I could helped you...
Phosphoric acid is used in the synthesis of aspirin as a catalyst to facilitate the esterification reaction between salicylic acid and acetic anhydride. It helps increase the reaction rate and yield of aspirin.
The catalyst commonly used in making polyesters is an esterification catalyst, such as an acid catalyst like sulfuric acid or an organic acid like p-toluenesulfonic acid. These catalysts help facilitate the reaction between the diol and the dicarboxylic acid to form the polyester polymer.
Acetylsalicylic acid, better known as aspirin, has an approximate pH of 3 to 4.
By making the pellets porous, you maximize the surface to volume ratio of the catalyst, which allows you to use less of it, but get the same effect.
The ingredients needed to produce aspirin are salicylic acid and acetic anhydride. Acetic acid is also produced as a byproduct during the chemical reaction.
Aspirin is made when salicylic acid and acetic anhydride is reacted in the presence of an acid catalyst such as H2SO4. Acetylsalicylic acid (aspirin) and acetic acid is formed. The reaction is an esterification reaction.
Phosphoric acid is used in the synthesis of aspirin as a catalyst to facilitate the esterification reaction between salicylic acid and acetic anhydride. It helps increase the reaction rate and yield of aspirin.
The process of making aspirin in pharmaceutical manufacturing involves combining salicylic acid with acetic anhydride in the presence of a catalyst, such as sulfuric acid. This reaction forms acetylsalicylic acid, which is the active ingredient in aspirin. The mixture is then purified, crystallized, and dried to produce the final aspirin product. Quality control measures are implemented throughout the process to ensure the purity and consistency of the aspirin tablets.
Yes. ^ Well to improve on this, in simple terms. A catalyst is something that brings on the reaction, in this case the liquid catalyst can only contain a little amount of water otherwise side reactions will occur and this would impact (reduce) the yield of aspirin - not good, sulfuric acid is usually used because it is 98% pure, phosphoric acid can also be used but it is only about 85% pure, still OK. HCL in its most concentrated form is only 37% pure and there fore no good at all. In a shorter to the point answer, H2SO4 is a pure catalyst which will give you a close to accurate yield of aspirin.
A substance which helps with chemical reactions, by making them possible at all, or reducing the effort required, is a catalyst.
The catalyst commonly used in making polyesters is an esterification catalyst, such as an acid catalyst like sulfuric acid or an organic acid like p-toluenesulfonic acid. These catalysts help facilitate the reaction between the diol and the dicarboxylic acid to form the polyester polymer.
Acetylsalicylic acid, better known as aspirin, has an approximate pH of 3 to 4.
it is cocaine
Hcl cl- is a strong nucleophile capible of substituting the oH group of the salicyclic acid,, my best guess
By making the pellets porous, you maximize the surface to volume ratio of the catalyst, which allows you to use less of it, but get the same effect.
The ingredients needed to produce aspirin are salicylic acid and acetic anhydride. Acetic acid is also produced as a byproduct during the chemical reaction.
because it has the word cat in it